Two related studies report JWST/MIRI spectroscopy of protoplanetary disks in the Upper Scorpius association, which is older than many previous JWST/MIRI targets. One analysis observes 14 disks in Upper Scorpius (about 5–10 million years) and models their inner-disk gas with slab emission under local thermal equilibrium. It finds that roughly half show detectable molecular emission beyond H2 (including H2O, CO2, HCN, C2H2 and H2), while the other half are molecular-poor and show no molecular lines other than H2. When combined with additional Upper Scorpius data from the AGE-PRO program, the studies find lower detection rates and systematically lower line luminosities for major molecular species than in younger (about 1–3 million years) comparison disks, with different scaling against accretion luminosity. The second study presents JWST/MIRI MRS results for 10 disks aged about 2–6 million years, finding large diversity in chemical compositions and a strong reduction in water: water luminosities are lower by factors of about 10 to 1000. Both works interpret the trends as evidence for chemical evolution in the inner disk, with cooler emitting layers, reduced inner-disk molecular gas masses, and indications of elevated inner-disk C/O in older systems.