Health regulation is at the center of today’s headlines after FDA Commissioner Marty Makary resigned following just 13 turbulent months, capping weeks of reported pressure from the White House, Congress, industry and advocacy groups over the agency’s direction on issues from food policy to vaping oversight. His exit, with senior official Kyle Diamantas set to serve as acting commissioner, adds to a sense of instability across federal health agencies at a moment when public-health leadership is already under strain. The broader backdrop is one of geopolitical pressure rippling into everyday systems: the Pentagon says the Iran conflict has now cost the U.S. about $29 billion, while supply disruptions tied to the war are forcing Japan’s Calbee to shift some snack packaging to black and white because ink materials are harder to source. Together, the stories underscore how political turbulence is reshaping both health governance and the wider economy.