A two-car rear-end collision on Highway 401 in Mississauga, Ontario leaves two people dead and three others injured, according to reports. The crash involves vehicles traveling on the highway and occurs in Mississauga. Emergency crews respond at the scene and provide medical assistance. Three injured people are transported to hospital for treatment. The reports indicate the incident results in fatalities and multiple injuries, but they do not provide further details on the cause of the collision, the identities of those involved, or the exact location or time of day. Authorities continue to deal with the aftermath of the crash, including responding to injuries and managing the scene, though the sources provided do not describe additional follow-up such as investigation updates, charges, or traffic impacts.