A new trailer for Zach Cregger’s upcoming Resident Evil movie has been released, offering another look at the game-based horror film starring Austin Abrams. The footage follows Abrams’ character, Bryan, described as an inept medical courier who is hired to deliver organs to “Raccoon City General,” a facility positioned “outside the zone.” The mission pays double, but Bryan’s trip rapidly spirals into violence and chaos as Raccoon City becomes overrun by infected people.

Cregger’s film is presented as an “entirely original story” set within the Resident Evil universe and tied to the Raccoon City Incident, while using a new protagonist rather than adapting a specific game plotline. The trailer also emphasizes connections to the games through visual motifs and references, including red-and-white branding elements associated with Umbrella Corporation, shotgun-like weapon imagery, and a brief appearance of classic typewriter “save point” iconography.

The movie is scheduled to open in theaters on September 18. Cregger has said he aimed to create a film that feels distinctively “Zach,” while still rewarding fans with recognizable nods to the series.