Former NFL running back Joe Mixon is reportedly facing an uncertain future after a foot injury that has kept him out of play. Yahoo Sports reports that the injury sidelines him for the entire 2025 season and says Mixon’s career is “likely over,” implying he may not return to the league. Newsweek similarly reports that Mixon has not appeared in an NFL game since January 2025 and frames his situation as possibly leading him to step away from the NFL. Both accounts tie the current status directly to the same foot injury and describe a prolonged absence from the sport. While the reports differ slightly in phrasing—one emphasizing that he is likely finished, the other noting he may walk away—they align on the core points that Mixon has been inactive since January 2025 and that his foot injury has prevented him from playing through 2025. The sources do not provide additional details about the injury’s cause, severity, or any confirmed return timetable, and they present their conclusions as reports rather than official team or league statements.