Jeff Dean, Google’s longtime AI scientist and one of the company’s earliest employees, is departing Alphabet after nearly 27 years to launch his own company, Discovery Loop, according to reporting cited by multiple outlets. Dean joined Google in 1999 as the company’s 30th employee and is described as a key figure in Google’s AI strategy, including work connected to Google Brain. The Wall Street Journal reports that Dean will serve as CEO of Discovery Loop, a public-benefit corporation. The startup initially targets machine-learning research and engineering, with plans to expand into hardware design and applications such as drug discovery and clean energy. Dean says the concept is to automate parts of the “experimental loop” using machine-learning models to augment human scientists and explore a broader space of experiments. Alphabet is reported to invest in the startup and provide cloud and computing capacity, while Radical Ventures and Khosla Ventures co-lead an initial seed round, though valuation was not disclosed. The WSJ also reports that Google researchers Oriol Vinyals, Quoc Le, and Sanjay Ghemawat are joining Dean at the new company. Alphabet shares reportedly fall after the announcement.