The U.S. government warns that the Medusa ransomware operation has breached more than 500 critical infrastructure organizations in the United States since June 2021. The assessment is attributed to an updated joint advisory that reflects FBI investigations conducted as late as April 2026.

The advisory is issued by CISA alongside the FBI and the Department of Health and Human Services (HHS), and it builds on a March 2025 advisory. Multiple outlets report that the number of impacted victims has grown over time, including an increase from more than 300 reported the prior year. Coverage also highlights that Medusa is operating as ransomware-as-a-service, recruiting affiliates and initial-access brokers and using stolen data to pressure victims into paying.

Outlets also emphasize evolving tactics that make defense harder, such as leveraging compromised access and advancing intrusion techniques. While details vary in emphasis, all describe the recommended defensive measures as focused on reducing exploitability of systems, limiting lateral movement inside networks, and restricting access to internal remote services from untrusted origins.