Oklahoma State quarterback Drew Mestemaker throws for 389 yards and three touchdowns as the Cowboys beat West Virginia 41-24 in their Big 12 opener on Saturday night. The Cowboys fall behind 14-3 early before rallying, improving to 3-1 for the first time since 2021. Caleb Hawkins rushes for 180 yards and a touchdown for Oklahoma State.

Mestemaker’s scoring passes include a 21-yard touchdown throw to Justin Bowick just before halftime. Multiple reports describe West Virginia’s defensive breakdowns allowing Oklahoma State to generate big plays. Across the coverage, West Virginia remains competitive for stretches, but Oklahoma State’s late surge and offensive production lead to the decisive 17-point margin at the end.