Joe Manganiello says a life-threatening autoimmune disease devastated his health and his marriage to Sofía Vergara. In excerpts and reporting ahead of the memoir “Bloodlines,” he describes worsening symptoms, emotional distance with Vergara, and how his condition affected decisions about having children. He also discusses adopting a chihuahua named Bubbles during a difficult period.

Manganiello also portrays the treatment and recovery process in his own account. The Los Angeles Times reports he says a Santa Monica shaman helped heal him after the illness nearly killed him and that his condition required major medical intervention, including “major organ amputation.” Other outlets focus more on how he links his deteriorating health to the breakdown of the relationship and accompanying public rumors.