Australian researchers report training lab-grown human brain cells to control a silicon system to play the 1990s video game “Doom.” The work uses “biological computer” setups in which living brain cells—grown from stem cells derived from human blood donations—are interfaced with a chip. According to the accounts, the researchers place roughly 200,000 neurons in each experimental device and use the cells’ activity as a way to influence the game controls. The team demonstrates that the neurons can learn to interact with the system in a way that produces gameplay outcomes, though the results are described as early and limited. The researchers say the experiment is a starting point and that it remains to be seen what more complex tasks neurons could perform in this chip-based configuration. Overall, the outlets characterize the study as proof-of-concept research exploring how cultured neurons can be connected to electronic hardware for interactive computing experiments.