Mayo Clinic’s Board of Trustees has elected Dr. Matthew R. Callstrom, a longtime internal leader, as the next president and CEO. The election is set to follow the tenure of current CEO Dr. Gianrico Farrugia, who is scheduled to remain in the role through the end of December 2026.

The sources frame Callstrom as an “insider” with experience tied to strategy and innovation, including work associated with AI at the health system in Rochester, Minnesota. Across the reporting, the main emphasis differs in what it highlights: one outlet focuses on Callstrom’s background in strategy and AI innovation, while another centers on the formal board announcement and the leadership transition timeline. Together, the coverage confirms the appointment and situates it within Mayo Clinic’s planned handover process.