Isabelle Sapherson-Moralee, known as “Izzy,” who worked as an estate agent, dies in April 2025 at age 22 after years of ketamine use. Reports state she developed a ketamine addiction and had chronic pain. Her mother says the drug should be reclassified as a Class A substance, arguing this could reduce access and harm. According to the account, she first started taking ketamine about five years before her death, and she weighed about 5 st 9 lb (39 kg) at the time of her death. The sources provided focus on the family’s call for stronger regulation and do not include details on any wider policy response, clinical evidence, or legal process. The information presented centers on the circumstances described by her mother, including the timeline of use, underlying chronic pain, and the allegation of addiction contributing to her death.