UniQure says the U.S. Food and Drug Administration has reversed its prior stance on the company’s experimental Huntington’s disease gene therapy, allowing UniQure to move toward a U.S. approval application before running a new study. Multiple outlets report that the FDA previously challenged elements of the company’s submission plan following a public dispute involving clinical-trial data. After the reversal, UniQure can pursue an FDA pathway to seek approval without first completing an additional study, which the company frames as a change from the agency’s earlier position. The news comes after months of heightened scrutiny and disagreement between UniQure and FDA leadership about the evidence needed for review. Investors reacted strongly to the announcement, with at least one report describing a sharp jump in UniQure’s share price. The outlets characterize the development as a significant shift in the regulatory process for the therapy, though the exact timing and remaining requirements for approval are not detailed in the provided summaries. Overall, the reporting converges on the core point: the FDA is now permitting UniQure to submit the Huntington’s treatment for approval following its earlier opposition.