The World Health Organization (WHO) issues its first comprehensive clinical management guidelines for filovirus diseases, covering all types of Ebola and Marburg viruses. The announcement comes as the Democratic Republic of the Congo (DRC) responds to an Ebola outbreak caused by the Bundibugyo virus. WHO’s guidance focuses on patient care in clinical settings and emphasizes early supportive treatment as a key factor in improving survival and health outcomes. The guidelines include 16 evidence-based recommendations intended to standardize care across different filovirus infections and treatment contexts. While the WHO describes the recommendations as applicable to Ebola and Marburg broadly, it also notes the immediate relevance to ongoing outbreak response in the DRC. The publication reflects WHO’s role in providing technical direction during outbreaks, including detailed approaches for healthcare providers. The guidelines aim to support consistent, evidence-based clinical decision-making for patients with suspected or confirmed filovirus disease, regardless of the specific Ebola or Marburg virus involved.