The Buffalo Bills are set to officially open Highmark Stadium as their new home with a nationally televised game against the Detroit Lions. Multiple outlets report that the matchup is scheduled for Thursday, Sept. 17, in Week 2 of the upcoming NFL regular season. The game is designated as a Thursday Night Football broadcast, making it the season’s first Thursday night game, according to The Athletic. Both sources describe Highmark Stadium as the venue for the Bills’ home debut, framing it as a formal opening tied to the Week 2 kickoff against Detroit. The announcement also specifies the opponent and date, placing the event within the league’s early-season schedule. Overall, the coverage converges on the same core details: the Bills’ new stadium, the Lions as the visiting opponent, and the Thursday night national TV designation for their Week 2 opener on Sept. 17.