NBC’s “St. Denis Medical” brings back an “In Living Color” connection as Damon Wayans guest-stars in the show’s Season 3 premiere. Wayans appears as Dr. Highland, described as a “charming but pompous” doctor who fills in while Ron is away, with David Alan Grier reprising his role as Ron.
All three outlets report that the casting reflects a reunion between Wayans and Grier, who previously worked together on “In Living Color.” Variety and Deadline highlight the reunion aspect and describe Wayans’ character, including his role as a temporary substitute doctor at St. Denis. The Hollywood Reporter similarly notes that the network books Wayans for a guest appearance opposite Grier, framing it as another pairing of the two veteran performers. Deadline also references a first-look photo tied to the premiere.
Overall, the sources agree that the collaboration is limited to the Season 3 opener and is presented as a character-driven cameo rather than a broader casting change.