Researchers report that urolithin A—a compound the body can produce after eating foods such as pomegranates, walnuts, and some berries—improves heart function in preclinical models of hard-to-treat heart failure. In animal studies, measures of heart function improve by up to 80%. The compound is described as helping stiff heart tissue relax, reducing scarring, and limiting abnormal enlargement.
The studies also include tests in engineered human heart tissue, where urolithin A is said to improve relaxation. ScienceDaily and Times of India both focus on the same proposed biological effects—greater tissue relaxation and less damage-linked remodeling—while describing the work as an early-stage investigation based on animal and laboratory tissue models rather than clinical trials in people.
